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Sporotrichosis should be how is it treated?

January 23rd, 2010 kevin Leave a comment Go to comments

(A) treatment
1. Inside the medication
(1) iodide: 5% ~ 10% potassium iodide 3g / d, can be gradually increased to 6 ~ 8g / d, the damage can be following the suit disappears 2 to 4 weeks, the general course of 2 to 3 months. Potassium iodide saturated solution 10 drops / time, 3 times / d, can be gradually increased to 40 drops, 3 times / d, usually 1 week are effective, 1 ~ 2 months curable. Oral potassium iodide have indigestion or nausea, vomiting, poor appetite and other gastrointestinal reactions, can be used sodium iodide 1g / d intravenous injection. If patients have tuberculosis, potassium iodide should not be applied.
(2) griseofulvin: less effective, generally do not. Those who are allergic to iodine may consider, 0.8g / d, for 1 ~ 3 months.
(3) Flucytosine: According to 100 ~ 200mg/kg body weight, until cured.
(4) Itraconazole: ① lymphatic tube: 100 ~ 200mg / d, for 3 to 6 months; ② fixed: 50 ~ 100mg / d, for 3 to 6 months.
(5) Terbinafine: 2 times / d, each 0.25g, generally serving a ~ 2 months.
(6) Fluconazole: 200 ~ 400mg / d.
(7) of amphotericin B on the skin type and disseminated lymphatic sporotrichosis can be applied. The first dose of 3 ~ 5mg, adults can be added to the 30 ~ 35mg, continuing a ~ 2 months.
2. For external use 2% potassium iodide or 0.2% iodine solution can be topical; 2% dimethyl sulfoxide ball erythromycin penetration agent, 2 times / d; amphotericin B250 ~ 500mg, dimethyl sulfoxide 30ml, glycerol 20ml, water 50m1, formulated into a thoroughly topical agent; thermotherapy local heating heater 45 ℃, 3 times / d, every 60min, for the effective isolation of the damage.
(B) the prognosis
Cutaneous lymphatic type, nodules gradually softening, ulceration of the formation of chronic ulcers, difficult to heal. More after the formation of scar.

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