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Diphtheria should be how to prevent?

January 19th, 2010 kevin No comments

Should adopt comprehensive measures based vaccination.
1.  isolate and treat patients until the symptoms disappeared after two times of nasopharyngeal culture negative. If no culture conditions, in the full treatment cases, the patients to lift the quarantine period of 2 weeks. Pairs of close contact with the nasopharynx should be done to nurture and observe for 7 days. Did not receive full immunization of children, it is best to refined diphtheria toxoid and anti-toxin injection at the same time. During the prevalence of nurseries and primary schools should be carefully carried out morning checks. Active treatment carriers. With ordinary doses of penicillin treatment of 5 to 7 days. The collective institutions for children and adults should stay in contact with police seven days, and to make the nose throat culture and diphtheria toxin test. Adult close contacts should also make these checks. ① culture and toxin tests were positive as the treatment of diphtheria cases should be isolated for observation and treatment with penicillin, once the symptoms or with anti-toxin. ② culture positive, toxin tests were positive as the treatment of diphtheria cases. ③ culture and toxin testing were negative may lift the stay Review. ④ culture-negative, toxin test positive, they should give vaccinations.
2. Cut off the transmission of patient contact with the goods and secretion of excreta, can double the volume of 20% chlorine lime emulsion soak 1h, or chlorine disinfectants 5000 × 10-6 soak 30min.
3. Enhance the immunity auto-immune: Available white, 100, breaking hybrid vaccine or adsorbed diphtheria toxoid vaccination refined. Passive immunization: diphtheria-susceptible because of infirmity or illness can not accept the diphtheria toxoid vaccination against diphtheria but contact with patients, can antitoxin. 1000 ~ 20000U intramuscular injection of adult, pediatric 1000U, valid for only 2 ~ 3 weeks. The human body’s immunity against diphtheria. Determined by blood levels of anti-toxin. Serum containing 10U / L that has a protective effect. Can be used diphtheria toxin (Sikh) test, or indirect hemagglutination test and ELISA assay of serum anti-toxin levels of the crowd to see the crowd of anti-toxin levels, can help predict the potential and extent of the diphtheria epidemic can also detect the effect of vaccination .The level of population immunity levels were negatively correlated with the incidence rate. China’s anti-toxin levels in some areas has reached 85% ~ 95%. These countries are not diphtheria epidemic.

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